Growing up with Prader-Willi syndrome

Prader-Willi syndrome is a neurodevelopmental genetic disease characterised by gradual and multi-dimensional clinical progression with various stages of development.

From early infancy, changes in feeding behaviour are described, with growing interest in food and the appearance of hyperphagia associated with an impaired sense of satiety, which can lead to morbid obesity in adolescence and adulthood.

Associated disorders may be observed at different ages of life, including learning difficulties, behaviour and social skills disorders, as well as endocrine dysfunctions and, in some cases, persistent swallowing disorders. These manifestations are part of the specific neurodevelopmental course of Prader-Willi Syndrome and contribute to the complexity of its medical management.