Preclinical Studies

Proof of concept

(Schaller et al., 2010 ; Meziane et al., 2015)

Neonatal administration of oxytocin to Magel2 KO mice (PW-like) 

Preclinical studies were conducted in animal models of Prader-Willi syndrome, particularly in Magel2 KO mice (‘Prader-Willi-like’), to explore the role of the oxytocinergic system in early development (CNRS, INMED – INSERM).